RARE! "Biochemist" Choh Hao Li Hand Signed 3.5X5.5 Card Todd Mueller COA

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RARE! "Biochemist" Choh Hao Li Hand Signed 3.5X5.5 Card.
This item is certified authentic by Todd Mueller Autographs and comes with their Certificate of Authenticity.
ES-4073E
Choh Hao Li
(sometimes
Cho Hao Li
) (
Chinese
:
李卓皓
;
pinyin
:
Lǐ Zhuōhào
; April 21, 1913 – November 28, 1987) was a Chinese-born American biochemist who discovered, in 1966, that human
pituitary
growth
hormone
(
somatotropin
) consists of a chain of 256
amino acids
. In 1970 he succeeded in synthesizing this hormone, the largest protein
molecule
synthesized
up to that time. Li was born in
Guangzhou
and educated at the
Nanjing University
. In 1935 he immigrated to the US, where he took up postgraduate studies at the
University of California, Berkeley
and later joined the staff. He became professor in 1950. In 1955 he was elected as Academician of
Academia Sinica
, Republic of China. Li spent his entire academic career studying the pituitary-gland hormones. In collaboration with various co-workers, he isolated several protein hormones, including
adrenocorticotropic hormone
(ACTH), which stimulates the
adrenal cortex
to increase its secretion of
corticoids
. In 1956, Li and his group showed that ACTH consists of 39 amino acids arranged in a specific order, and that the whole chain of the natural hormone is not necessary for its action. He isolated another pituitary hormone called
melanocyte-stimulating hormone
(MSH) and found that not only does this hormone produce some effects similar to those produced by ACTH, but also that part of the amino acid chain of MSH is the same as that of ACTH.